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A Method for Delineation of Bone Surfaces in Photoacoustic Computed Tomography of the Finger

Biswas, SK and van Es, P and Steenbergen, W and Manohar, S (2016) A Method for Delineation of Bone Surfaces in Photoacoustic Computed Tomography of the Finger. In: ULTRASONIC IMAGING, 38 (1, SI). pp. 63-76.

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Official URL: http://dx.doi.org/10.1177/0161734615589288


Photoacoustic (PA) imaging of interphalangeal peripheral joints is of interest in the context of using the synovial membrane as a surrogate marker of rheumatoid arthritis. Previous work has shown that ultrasound (US) produced by absorption of light at the epidermis reflects on the bone surfaces within the finger. When the reflected signals are backprojected in the region of interest, artifacts are produced, confounding interpretation of the images. In this work, we present an approach where the PA signals known to originate from the epidermis are treated as virtual US transmitters, and a separate reconstruction is performed as in US reflection imaging. This allows us to identify the bone surfaces. Furthermore, the identification of the joint space is important as this provides a landmark to localize a region-of-interest in seeking the inflamed synovial membrane. The ability to delineate bone surfaces allows us to identify not only the artifacts but also the interphalangeal joint space without recourse to new US hardware or a new measurement. We test the approach on phantoms and on a healthy human finger.

Item Type: Journal Article
Additional Information: Copy right for this article belongs to the SAGE PUBLICATIONS INC, 2455 TELLER RD, THOUSAND OAKS, CA 91320 USA
Keywords: photoacoustic tomography; photoacoustically induced ultrasound; bone delineation; finger
Department/Centre: Division of Physical & Mathematical Sciences > Instrumentation Appiled Physics
Date Deposited: 22 Jan 2016 05:32
Last Modified: 22 Jan 2016 05:32
URI: http://eprints.iisc.ac.in/id/eprint/53141

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