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The interface makes a difference: lanthanide ion coated vesicles hydrolyze phosphodiesters

Poznik, Michal and Maitra, Uday and Koenig, Burkhard (2015) The interface makes a difference: lanthanide ion coated vesicles hydrolyze phosphodiesters. In: ORGANIC & BIOMOLECULAR CHEMISTRY, 13 (38). pp. 9789-9792.

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Official URL: http://dx.doi.org/10.1039/c5ob01265a


Lanthanide ions are strong Lewis acids. Their complexation to a variety of ligands can further enhance their Lewis acidity allowing the hydrolysis of phosphoesters and even DNA. We show that the interaction of lanthanide ions with vesicles from zwitterionic phosphatidylcholine lipids gives supramolecular structures in which the metal ion is loosely coordinated to the surface. This assembly provides a high density of Lewis-acidic metal centres, which hydrolyze phosphodiesters with enhanced rates.

Item Type: Journal Article
Additional Information: Copy right for this article belongs to the ROYAL SOC CHEMISTRY, THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND
Department/Centre: Division of Chemical Sciences > Organic Chemistry
Date Deposited: 31 Oct 2015 05:34
Last Modified: 31 Oct 2015 05:34
URI: http://eprints.iisc.ac.in/id/eprint/52619

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