Iodine promoted alpha-hydroxylation of ketones

Siddaraju, Yogesh and Prabhu, Kandikere Ramaiah (2015) Iodine promoted alpha-hydroxylation of ketones. In: ORGANIC & BIOMOLECULAR CHEMISTRY, 13 (24). pp. 6749-6753.

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Abstract

A novel method for alpha-hydroxylation of ketones using substoichiometric amount of iodine under metalfree conditions is described. This method has been successfully employed in synthesizing a variety of heterocyclic compounds, which are useful precursors. alpha-Hydroxylation of diketones and triketones are illustrated. This strategy provides a novel, efficient, mild and inexpensive method for alpha-hydroxylation of aryl ketones using a sub-stoichiometric amount of molecular iodine.

Item Type:	Journal Article
Publication:	ORGANIC & BIOMOLECULAR CHEMISTRY
Publisher:	ROYAL SOC CHEMISTRY
Additional Information:	Copy right for this article belongs to the ROYAL SOC CHEMISTRY, THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND
Department/Centre:	Division of Chemical Sciences > Organic Chemistry
Date Deposited:	19 Jul 2015 09:42
Last Modified:	19 Jul 2015 09:42
URI:	http://eprints.iisc.ac.in/id/eprint/51899

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