A Mild Protocol for the Regioselective Ring Opening of Doubly Activated Cyclopropanes by Using Selenolates Generated in Situ: Synthesis of Functionalized Organoselenium Compounds

Gopinath, Purushothaman and Chandrakala, RN and Chandrasekaran, Srinivasan (2015) A Mild Protocol for the Regioselective Ring Opening of Doubly Activated Cyclopropanes by Using Selenolates Generated in Situ: Synthesis of Functionalized Organoselenium Compounds. In: SYNTHESIS-STUTTGART, 47 (10). pp. 1488-1498.

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Abstract

A variety of functionalized organoselenium compounds were synthesized from doubly activated cyclopropanes and diselenides in the presence of sodium borohydride. A range of substituents were stable under these reaction conditions. Additionally, we extended the scope of the method by reducing nitro groups in the products to give the corresponding selenium-containing unnatural amino acids.

Item Type:	Journal Article
Publication:	SYNTHESIS-STUTTGART
Publisher:	GEORG THIEME VERLAG KG
Additional Information:	Copy right for this article belongs to the GEORG THIEME VERLAG KG, RUDIGERSTR 14, D-70469 STUTTGART, GERMANY
Keywords:	cyclopropanes; diselenides; selenium; amino acids; ring opening
Department/Centre:	Division of Chemical Sciences > Organic Chemistry
Date Deposited:	15 Jun 2015 07:14
Last Modified:	15 Jun 2015 07:14
URI:	http://eprints.iisc.ac.in/id/eprint/51651

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