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Recent advances in lipid molecular design

Bhattacharya, Santanu and Bajaj, Avinash (2005) Recent advances in lipid molecular design. In: Current Opinion in Chemical Biology, 9 (6). pp. 647-655.

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The area of lipid molecular design is attracting widespread interest among numerous research groups worldwide. Diverse lipid assemblies in aqueous media, such as vesicles, bilayers and nanorods, offer new applications in chemical biology. Lipids with specifically tailored molecular architecture have been successfully employed as gene delivery vehicles, for controlled drug release and the preparation of supramolecular gels. Such molecular design of lipids, as well as their characterization upon membrane formation, offers an insight into the possible molecular basis of their properties. This in turn helps in the design of further generations of lipid systems with more predictable characteristics. Here, we present an overview of the current trends in lipid design and their utilization in various biochemical, physical and chemical applications.

Item Type: Journal Article
Publication: Current Opinion in Chemical Biology
Publisher: Elsevier Science Ltd
Additional Information: Copyright for this article belongs to Elsevier.
Department/Centre: Division of Chemical Sciences > Organic Chemistry
Date Deposited: 19 Jan 2006
Last Modified: 19 Sep 2010 04:23
URI: http://eprints.iisc.ac.in/id/eprint/5162

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