The peptide NCbz-Val-Tyr-OMe and aromatic pi-pi interactions

Nicholas, Sumesh (2015) The peptide NCbz-Val-Tyr-OMe and aromatic pi-pi interactions. In: ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY, 71 (3). 211+.

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Abstract

The peptide N-benzyloxycarbonyl-L-valyl-L-tyrosine methyl ester or NCbz-Val-Tyr-OMe (where NCbz is N-benzyloxycarbonyl and OMe indicates the methyl ester), C23H28N2O6, has an extended backbone conformation. The aromatic rings of the Tyr residue and the NCbz group are involved in various attractive intra- and intermolecular aromatic - interactions which stabilize the conformation and packing in the crystal structure, in addition to NH...O and OH...O hydrogen bonds. The aromatic - interactions include parallel-displaced, perpendicular T-shaped, perpendicular L-shaped and inclined orientations.

Item Type:	Journal Article
Publication:	ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY
Publisher:	WILEY-BLACKWELL
Additional Information:	Copy right for this article belongs to the WILEY-BLACKWELL, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
Keywords:	tyrosine; valine; dipeptides; crystal structure; protein design; aromatic - interactions; weak interactions; hydrogen bonding
Department/Centre:	Division of Physical & Mathematical Sciences > Physics
Date Deposited:	29 Apr 2015 04:44
Last Modified:	29 Apr 2015 04:44
URI:	http://eprints.iisc.ac.in/id/eprint/51441

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