Chiral discrimination of secondary alcohols and carboxylic acids by NMR spectroscopy

Pal, Indrani and Chaudhari, Sachin Rama and Suryaprakash, Nagaraja Rao (2015) Chiral discrimination of secondary alcohols and carboxylic acids by NMR spectroscopy. In: MAGNETIC RESONANCE IN CHEMISTRY, 53 (2). pp. 142-146. (In Press)

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Abstract

The manuscript reports two novel ternary ion-pair complexes, which serve as chiral solvating agents, for enantiodiscrimination of secondary alcohols and carboxylic acids. The protocol for discrimination of secondary alcohols is designed by using one equivalent mixture each of enantiopure mandelic acid, 4-dimethylaminopyridine (DMAP) and a chiral alcohol. For discrimination of carboxylic acids, the ternary complex is obtained by one equivalent mixture each of enantiopure chiral alcohol, DMAP and a carboxylic acid. The designed protocols also permit accurate measurement of enantiomeric composition. Copyright (C) 2014 John Wiley & Sons, Ltd.

Item Type:	Journal Article
Publication:	MAGNETIC RESONANCE IN CHEMISTRY
Publisher:	WILEY-BLACKWELL
Additional Information:	Copy right for this article belongs to the WILEY-BLACKWELL, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
Keywords:	NMR spectroscopy; chiral discrimination; carboxylic acids; enatiomeric excess
Department/Centre:	Division of Chemical Sciences > Solid State & Structural Chemistry Unit
Date Deposited:	21 Apr 2015 07:01
Last Modified:	28 Feb 2019 11:56
URI:	http://eprints.iisc.ac.in/id/eprint/51312

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