Manna, Madhu Sudan and Mukherjee, Santanu (2015) Organocatalytic Enantioselective Formal C(sp(2))-H Alkylation. In: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 137 (1). pp. 130-133.
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Official URL: http://dx.doi.org/ 10.1021/ja5117556
Abstract
An organocatalytic enantioselective formal C(sp(2))-H alkylation is reported. This alkylative desymmetrization of prochiral 2,2-disubstituted cyclopentene-1,3-dione is catalyzed by a bifunctional tertiary aminourea derivative, utilizes air-stable and inexpensive nitroalkanes as the alkylating agents, and delivers synthetically versatile five-membered carbocycles containing an all-carbon quaternary stereogenic center remote from the reaction site in excellent enantioselectivity.
Item Type: | Journal Article |
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Publication: | JOURNAL OF THE AMERICAN CHEMICAL SOCIETY |
Publisher: | AMER CHEMICAL SOC |
Additional Information: | Copyright for this article belongs to the AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA |
Department/Centre: | Division of Chemical Sciences > Organic Chemistry |
Date Deposited: | 19 Mar 2015 12:08 |
Last Modified: | 19 Mar 2015 12:08 |
URI: | http://eprints.iisc.ac.in/id/eprint/51049 |
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