Synthesis and antioxidant activity study of pyrazoline carrying an arylfuran/arylthiophene moiety

Jois, Vidyashree HS and Kalluraya, Balakrishna and Girisha, Kotathattu S (2014) Synthesis and antioxidant activity study of pyrazoline carrying an arylfuran/arylthiophene moiety. In: JOURNAL OF THE SERBIAN CHEMICAL SOCIETY, 79 (12). 1469-S172.

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Abstract

A novel series of N-acetyl-3-aryl-5-(5-(p/o-nitrophenyl)-2-furyl//thienyl)-substituted pyrazolines (3a-o) were synthesized by the reaction of 1-aryl-3-(5-(p/o-nitrophenyl)-2-furyl/thienyl)-2-propene-1-ones with hydrazine hydrate in acetic acid medium. The structures of the newly synthesized compounds were established by IR, H-1-NMR, mass spectra and a single-crystal X-ray study. The antioxidant activities of the synthesized compounds were determined using the DPPH scavenging assay. The compounds 3a, 3f, 3h and 3o showed moderate activity.

Item Type:	Journal Article
Publication:	JOURNAL OF THE SERBIAN CHEMICAL SOCIETY
Publisher:	SERBIAN CHEMICAL SOC
Additional Information:	Copy right for this article belongs to the SERBIAN CHEMICAL SOC, KARNEGIJEVA 4, 11 120 BELGRADE, SERBIA
Keywords:	N-acetyl-3,5-disubstituted pyrazoline; antioxidant activity; arylfuran; arylthiophene
Department/Centre:	Division of Chemical Sciences > Solid State & Structural Chemistry Unit
Date Deposited:	05 Mar 2015 12:57
Last Modified:	05 Mar 2015 12:57
URI:	http://eprints.iisc.ac.in/id/eprint/51014

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