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Synthesis and Antioxidant Activities of Novel Chiral Ebselen Analogues

Elsherbini, Mohamed and Hamama, Wafaa S and Zoorob, Hanafi H and Bhowmick, Debasish and Mugesh, Govindasamy and Wirth, Thomas (2014) Synthesis and Antioxidant Activities of Novel Chiral Ebselen Analogues. In: HETEROATOM CHEMISTRY, 25 (5, SI). pp. 320-325.

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Official URL: http://dx.doi.org/ 10.1002/hc.21164


Novel chiral analogues of the antioxidant, anti-inflammatory organoselenium drug ebselen were synthesized. The reaction proceeded readily from 2-(chloroseleno)benzoyl chloride with chiral amino compounds. The chiral substituent on the nitrogen atom did not provide a substantial increase in activities and the newly synthesized compounds showed similar activities to ebselen.

Item Type: Journal Article
Additional Information: Copyright for this article belongs to the WILEY-BLACKWELL, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
Department/Centre: Division of Chemical Sciences > Inorganic & Physical Chemistry
Date Deposited: 20 Dec 2014 04:25
Last Modified: 20 Dec 2014 04:25
URI: http://eprints.iisc.ac.in/id/eprint/50474

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