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Study of phase synchronization in multichannel seizure EEG using nonlinear recurrence measure

Rangaprakash, D and Pradhan, N (2014) Study of phase synchronization in multichannel seizure EEG using nonlinear recurrence measure. In: BIOMEDICAL SIGNAL PROCESSING AND CONTROL, 11 . pp. 114-122.

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Official URL: http://dx.doi.org/10.1016/j.bspc.2014.02.012


Complex biological systems such as the human brain can be expected to be inherently nonlinear and hence difficult to model. Most of the previous studies on investigations of brain function have either used linear models or parametric nonlinear models. In this paper, we propose a novel application of a nonlinear measure of phase synchronization based on recurrences, correlation between probabilities of recurrence (CPR), to study seizures in the brain. The advantage of this nonparametric method is that it makes very few assumptions thus making it possible to investigate brain functioning in a data-driven way. We have demonstrated the utility of CPR measure for the study of phase synchronization in multichannel seizure EEG recorded from patients with global as well as focal epilepsy. For the case of global epilepsy, brain synchronization using thresholded CPR matrix of multichannel EEG signals showed clear differences in results obtained for epileptic seizure and pre-seizure. Brain headmaps obtained for seizure and preseizure cases provide meaningful insights about synchronization in the brain in those states. The headmap in the case of focal epilepsy clearly enables us to identify the focus of the epilepsy which provides certain diagnostic value. Comparative studies with linear correlation have shown that the nonlinear measure CPR outperforms the linear correlation measure. (C) 2014 Elsevier Ltd. All rights reserved.

Item Type: Journal Article
Additional Information: copyright for this article belongs to ELSEVIER SCI LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
Keywords: Recurrence plot; Phase synchronization; Correlation between probabilities of recurrence; Multichannel EEG; Linear correlation; Epileptic seizure; Brain headmap
Department/Centre: Division of Electrical Sciences > Electrical Communication Engineering
Date Deposited: 26 Jun 2014 09:21
Last Modified: 26 Jun 2014 09:21
URI: http://eprints.iisc.ac.in/id/eprint/49379

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