Remarkable influence of secondary catalyst site on enantioselective desymmetrization of cyclopentenedione

Manna, Madhu Sudan and Mukherjee, Santanu (2014) Remarkable influence of secondary catalyst site on enantioselective desymmetrization of cyclopentenedione. In: CHEMICAL SCIENCE, 5 (4). pp. 1627-1633.

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Abstract

An efficient, robust and highly enantioselective catalytic desymmetrization of 2,2-disubstituted cyclopentene-1,3-diones is developed via direct vinylogous nucleophilic addition of deconjugated butenolides. A remarkable influence of the secondary catalyst site on the enantioselectivity points towards an intriguing mechanistic scenario, possibly by triggering a change in catalyst conformation.

Item Type:	Journal Article
Publication:	CHEMICAL SCIENCE
Publisher:	ROYAL SOC CHEMISTRY
Additional Information:	Copyright for this article belongs to the ROYAL SOC CHEMISTRY, ENGLAND
Department/Centre:	Division of Chemical Sciences > Organic Chemistry
Date Deposited:	12 May 2014 05:36
Last Modified:	12 May 2014 05:36
URI:	http://eprints.iisc.ac.in/id/eprint/48922

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