Facile protocols for the configurational assignment of primary amines and hydroxy acids by NMR

Chaudhari, Sachin Rama and Suryaprakash, Nagaraja Rao (2014) Facile protocols for the configurational assignment of primary amines and hydroxy acids by NMR. In: NEW JOURNAL OF CHEMISTRY, 38 (2). pp. 790-794.

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Abstract

Three-component chiral derivatization protocols are proposed for the assignment of the absolute configurations of chiral primary amines and chiral hydroxy acids using H-1-NMR. The protocols involve simple mixing of the ternary components in CDCl3, followed by stirring for 15 min. The spectra can be recorded directly, without invoking any separation method, unlike many other chiral derivatizing agents. The protocols permit the analysis in less than 15 min, making them convenient and effective for the assignment of the absolute configurations of primary amines and hydroxy acids.

Item Type:	Journal Article
Publication:	NEW JOURNAL OF CHEMISTRY
Publisher:	ROYAL SOC CHEMISTRY
Additional Information:	Copyright for this article belongs to theROYAL SOC CHEMISTRY,ENGLAND
Department/Centre:	Division of Chemical Sciences > NMR Research Centre (Formerly Sophisticated Instruments Facility) Division of Chemical Sciences > Solid State & Structural Chemistry Unit
Date Deposited:	25 Feb 2014 10:14
Last Modified:	25 Feb 2014 10:14
URI:	http://eprints.iisc.ac.in/id/eprint/48467

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