Lanke, Veeranjaneyulu and Prabhu, Kandikere Ramaiah (2013) Regioselective Synthesis of 4-Substituted Indoles via C-H Activation: A Ruthenium Catalyzed Novel Directing Group Strategy. In: ORGANIC LETTERS, 15 (24). pp. 6262-6265.
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Official URL: http://dx.doi.org/10.1021/ol4031149
Abstract
A highly regioselective functionalization of indole at the C-4 position by employing an aldehyde functional group as a directing group, and Ru as a catalyst, under mild reaction conditions (open flask) has been uncovered. This strategy to synthesize 4-substituted indoles is important, as this class of privileged molecules serves as a precursor for ergot alkaloids and related heterocyclic compounds.
| Item Type: | Journal Article |
|---|---|
| Publication: | ORGANIC LETTERS |
| Publisher: | AMER CHEMICAL SOC |
| Additional Information: | Copyright for this article belongs to the AMER CHEMICAL SOC USA |
| Department/Centre: | Division of Chemical Sciences > Organic Chemistry |
| Date Deposited: | 03 Feb 2014 11:29 |
| Last Modified: | 03 Feb 2014 11:29 |
| URI: | http://eprints.iisc.ac.in/id/eprint/48300 |
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