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Classification of Myopathies on Molecular basis in Drosophila using Raman spectroscopy

Gautam, Rekha and Vanga, Sandeep and Madan, Aditi and Nongthomba, Upendra and Umapathy, Siva (2013) Classification of Myopathies on Molecular basis in Drosophila using Raman spectroscopy. In: FOURTH ASIAN SPECTROSCOPY CONFERENCE, 15-18 December, 2013, NTU, Singapore.

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Myopathies are muscular diseases in which muscle fibers degenerate due to many factors such as nutrient deficiency, infection and mutations in myofibrillar etc. The objective of this study is to identify the bio-markers to distinguish various muscle mutants in Drosophila (fruit fly) using Raman Spectroscopy. Principal Components based Linear Discriminant Analysis (PC-LDA) classification model yielding >95% accuracy was developed to classify such different mutants representing various myopathies according to their physiopathology.

Item Type: Conference Poster
Keywords: Raman Spectroscopy, Principal Component Analysis, Linear Discriminant Analysis, Drosophila, myopathy
Department/Centre: Division of Biological Sciences > Molecular Reproduction, Development & Genetics
Division of Chemical Sciences > Inorganic & Physical Chemistry
Date Deposited: 30 Dec 2013 12:41
Last Modified: 30 Dec 2013 12:41
URI: http://eprints.iisc.ac.in/id/eprint/48089

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