Makwana, Kamlesh Madhusudan and Raghothama, Srinivasarao and Mahalakshmi, Radhakrishnan (2013) Stabilizing effect of electrostatic vs. aromatic interactions in diproline nucleated peptide beta-hairpins. In: PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 15 (37). pp. 15321-15324.
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Official URL: http://dx.doi.org/10.1039/c3cp52770k
Abstract
The contribution of Tyr-His vs. Cys-His interacting pairs to the scaffold stability of (D)Pro-(L)Pro nucleated peptide beta-hairpins has been examined. We present direct evidence for the superiority of the Cys-His pairs, mediated by sulphur-imidazole interactions, as added stabilizing agents of the beta-hairpin scaffold.
Item Type: | Journal Article |
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Publication: | PHYSICAL CHEMISTRY CHEMICAL PHYSICS |
Publisher: | ROYAL SOC CHEMISTRY |
Additional Information: | Copyright of this Article belongs to RSC |
Department/Centre: | Division of Chemical Sciences > NMR Research Centre (Formerly Sophisticated Instruments Facility) |
Date Deposited: | 08 Oct 2013 11:24 |
Last Modified: | 08 Oct 2013 11:24 |
URI: | http://eprints.iisc.ac.in/id/eprint/47455 |
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