Facile synthesis of isochromanones and isoquinolones by AuCl3 catalyzed cascade triggered by an internal nucleophile

Prasad, Kavirayani R and Nagaraju, Chinta (2013) Facile synthesis of isochromanones and isoquinolones by AuCl3 catalyzed cascade triggered by an internal nucleophile. In: Organic Letters, 15 (11). pp. 2778-2781.

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Abstract

Synthesis of isochromanones and isoquinolones comprising a quaternary center with high diastereoselectivity was realized via a AuCl3 catalyzed tandem intramolecular exo-dig heterocyclization/enol isomerization/Claisen rearrangement sequence in excellent yields. The reaction is general and amenable for the synthesis of structurally diverse analogues.

Item Type:	Journal Article
Publication:	Organic Letters
Publisher:	American Chemical Society
Additional Information:	Copyright of this article belongs to American Chemical Society.
Department/Centre:	Division of Chemical Sciences > Organic Chemistry
Date Deposited:	03 Sep 2013 07:09
Last Modified:	03 Sep 2013 07:09
URI:	http://eprints.iisc.ac.in/id/eprint/46976

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