Analytical solutions for diffuse fluorescence spectroscopy/imaging in biological tissues. Part II: comparison and validation

Ayyalasomayajula, Kalyan Ram and Yalavarthy, Phaneendra K (2013) Analytical solutions for diffuse fluorescence spectroscopy/imaging in biological tissues. Part II: comparison and validation. In: JOURNAL OF THE OPTICAL SOCIETY OF AMERICA A-OPTICS IMAGE SCIENCE AND VISION, 30 (3). pp. 553-559.

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Abstract

The analytical solutions for the coupled diffusion equations that are encountered in diffuse fluorescence spectroscopy/ imaging for regular geometries were compared with the well-established numerical models, which are based on the finite element method. Comparison among the analytical solutions obtained using zero boundary conditions and extrapolated boundary conditions (EBCs) was also performed. The results reveal that the analytical solutions are in close agreement with the numerical solutions, and solutions obtained using EBCs are more accurate in obtaining the mean time of flight data compared to their counterpart. The analytical solutions were also shown to be capable of providing bulk optical properties through a numerical experiment using a realistic breast model. (C) 2013 Optical Society of America

Item Type:	Journal Article
Publication:	JOURNAL OF THE OPTICAL SOCIETY OF AMERICA A-OPTICS IMAGE SCIENCE AND VISION
Publisher:	OPTICAL SOC AMER
Additional Information:	Copyright for this article belongs to the OPTICAL SOC AMER, USA.
Department/Centre:	Division of Interdisciplinary Sciences > Supercomputer Education & Research Centre
Date Deposited:	17 Apr 2013 05:53
Last Modified:	17 Apr 2013 05:53
URI:	http://eprints.iisc.ac.in/id/eprint/46396

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