Differential reflectance modulation sensing with diffractive microstructures

Kumawat, N and Varma, MM (2012) Differential reflectance modulation sensing with diffractive microstructures. In: APPLIED PHYSICS LETTERS, 101 (19).

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Abstract

We present a method for differential ratiometric measurement of reflectance change due to molecular adsorption using a diffractive microstructure fabricated on a reflectance contrast enhancing substrate for bulk refractometry and surface molecular binding detection applications. The differential method suppresses signal fluctuations due to thermal or concentration gradients in the sample flow cell by more than 40x and enables the real-time measurement of molecular interactions on the surface with a noise floor of about 70 pm. (V)C 2012 American Institute of Physics. http://dx.doi.org/10.1063/1.4766190]

Item Type:	Journal Article
Publication:	APPLIED PHYSICS LETTERS
Publisher:	AMER INST PHYSICS
Additional Information:	Copyright for this article belongs to AMER INST PHYSICS, MELVILLE, USA
Keywords:	adsorption;optical sensors;reflectivity;refractive index measurement
Department/Centre:	Division of Electrical Sciences > Electrical Communication Engineering > Electrical Communication Engineering - Technical Reports Division of Interdisciplinary Sciences > Centre for Nano Science and Engineering
Date Deposited:	02 Jan 2013 07:42
Last Modified:	02 Jan 2013 07:42
URI:	http://eprints.iisc.ac.in/id/eprint/45586

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