Quantitative estimation of mechanical and optical properties from ultrasound assisted optical tomography data

Singh, Mayanglambam Suheshkumar and Rajan, Kanhirodan and Vasu, Ram Mohan and Roy, Debasish (2012) Quantitative estimation of mechanical and optical properties from ultrasound assisted optical tomography data. In: Journal of Biomedical Optics, 17 (10). pp. 101507-1.

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Abstract

We demonstrate quantitative optical property and elastic property imaging from ultrasound assisted optical tomography data. The measurements, which are modulation depth M and phase phi of the speckle pattern, are shown to be sensitively dependent on these properties of the object in the insonified focal region of the ultrasound (US) transducer. We demonstrate that Young's modulus (E) can be recovered from the resonance observed in M versus omega (the US frequency) plots and optical absorption (mu(a)) and scattering (mu(s)) coefficients from the measured differential phase changes. All experimental observations are verified also using Monte Carlo simulations. (c) 2012 Society of Photo-Optical Instrumentation Engineers (SPIE). DOI: 10.1117/1.JBO.17.10.101507]

Item Type:	Journal Article
Publication:	Journal of Biomedical Optics
Publisher:	International Society for Optical Engineering
Additional Information:	Copyright of this article belongs to International Society for Optical Engineering.
Keywords:	Absorption Coefficient; Scattering Coefficient; Synchronized Speckle Detection; Ultrasound Assisted Optical Tomography
Department/Centre:	Division of Mechanical Sciences > Civil Engineering Division of Physical & Mathematical Sciences > Instrumentation Appiled Physics Division of Physical & Mathematical Sciences > Physics
Date Deposited:	20 Feb 2013 08:55
Last Modified:	20 Feb 2013 08:55
URI:	http://eprints.iisc.ac.in/id/eprint/45386

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