ePrints@IIScePrints@IISc Home | About | Browse | Latest Additions | Advanced Search | Contact | Help

Total Synthesis of (+)-Eburnamonine

Prasad, Kavirayani R and Nidhiry, John E. (2012) Total Synthesis of (+)-Eburnamonine. In: SYNLETT, 23 (10). pp. 1477-1480.

[img] PDF
synlett_23-10_1477-1480_2012.pdf - Published Version
Restricted to Registered users only

Download (186kB) | Request a copy
[img]
Preview
PDF
synlett_23-10_1477-1480-supp_2012.pdf

Download (1MB) | Preview
Official URL: http://dx.doi.org/10.1055/s-0031-1291143

Abstract

The enantiospecific total synthesis of vinca alkaloid (+)-eburnamonine is accomplished from L-ethyl lactate. Key feature of the synthesis is the construction of the chiral quaternary center involving a Johnson-Claisen rearrangement and assembly of the pentacyclic core by the Pictet-Spengler reaction and ring-closing metathesis.

Item Type: Journal Article
Publication: SYNLETT
Publisher: GEORG THIEME VERLAG KG
Additional Information: Copyright for this article belongs to Georg Thieme Verlag KG
Keywords: eburnamonine; alkaloids; L-ethyl lactate
Department/Centre: Division of Chemical Sciences > Organic Chemistry
Date Deposited: 23 Jul 2012 12:13
Last Modified: 23 Jul 2012 12:15
URI: http://eprints.iisc.ac.in/id/eprint/44808

Actions (login required)

View Item View Item