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Demonstration of a microfluidic polarimeter

Rajan, Rajitha Papukutty and Ghosh, Ambarish (2012) Demonstration of a microfluidic polarimeter. In: Conference on Frontiers in Biological Detection - From Nanosensors to Systems IV L, JAN 21-22, 2012 , San Francisco, CA, USA.

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Official URL: http://dx.doi.org/10.1117/12.908347


Traditional methods of detecting chiral molecules, such as optical rotation are not suitable for miniaturization, since, the magnitude of the rotation of polarization scales down linearly with the optical path length of the device. Since the origin of optical activity is due to difference of refractive indices between the two circularly polarized states of light, it is possible to detect chiral media by measuring the dependence of the angles of refraction on the polarization state of the incident light. This however is a weak effect and hence requires sensitive optical detection schemes, based on novel polarization modulation techniques. The device can be scaled down for applications involving small sample volumes. Fabrication details of a prototype microfluidic device are described.

Item Type: Conference Proceedings
Series.: Proceedings of SPIE
Additional Information: Conference on Frontiers in Biological Detection - From Nanosensors to Systems IV, San Francisco, CA, JAN 21-22, 2012
Department/Centre: Division of Electrical Sciences > Electrical Communication Engineering
Date Deposited: 05 Jul 2012 07:55
Last Modified: 06 Jul 2012 09:54
URI: http://eprints.iisc.ac.in/id/eprint/44778

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