Ag@AgI, Core@Shell Structure in Agarose Matrix as Hybrid: Synthesis, Characterization, and Antimicrobial Activity

Ghosh, Somnath and Saraswathi, A and Indi, SS and Hoti, SL and Vasan, HN (2012) Ag@AgI, Core@Shell Structure in Agarose Matrix as Hybrid: Synthesis, Characterization, and Antimicrobial Activity. In: LANGMUIR, 28 (22). pp. 8550-8561.

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Abstract

A novel in situ core@shell structure consisting of nanoparticles of Ag (Ag Nps) and AgI in agarose matrix (Ag@ AgI/agarose) has been synthesized as a hybrid, in order to have an efficient antibacterial agent for repetitive usage with no toxicity. The synthesized core@shell structure is very well characterized by XRD, UV-visible, photoluminescence, and TEM. A detailed antibacterial studies including repetitive cycles are carried out on Gram-negative Escherichia coli (E. coli) and Gram-positive Staphylococcus aureus (S. aureus) bacteria in saline water, both in dark and on exposure to visible light. The hybrid could be recycled for the antibacterial activity and is nontoxic toward human cervical cancer cells (HeLa cells). The water insoluble Ag@AgI in agarose matrix forms a good coating on quartz, having good mechanical strength. EPR and TEM studies are carried out on the Ag@AgI/agarose and the bacteria, respectively, to elucidate a possible mechanism for killing of the bacteria.

Item Type:	Journal Article
Publication:	LANGMUIR
Publisher:	AMER CHEMICAL SOC
Additional Information:	Copyright for this article belongs to American Chemical Society
Department/Centre:	Division of Biological Sciences > Microbiology & Cell Biology Division of Chemical Sciences > Solid State & Structural Chemistry Unit
Date Deposited:	07 Jul 2012 08:18
Last Modified:	07 Jul 2012 08:18
URI:	http://eprints.iisc.ac.in/id/eprint/44760

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