Application of vibrational microspectroscopy to biology and medicine

Singh, Bhawana and Gautam, Rekha and Kumar, Srividya and Kumar, Vinay BN and Nongthomba, Upendra and Nandi, Dipankar and Mukherjee, Geetashree and Santosh, Vani and Somasundaram, Kumaravel and Umapathy, Siva (2012) Application of vibrational microspectroscopy to biology and medicine. In: Current Science (Bangalore), 102 (2). pp. 232-244.

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Abstract

Vibrational microspectroscopic (Raman and infrared (IR)) techniques are rapidly emerging as effective tools to probe the basic processes of life. This review mainly focuses on the applications of Raman and IR microspectroscopy to biology and biomedicine, ranging from studies on cellular components in single cells to advancement in techniques for in vitro to in vivo applications. These techniques have proved to be instrumental in studying the biological specimen with minimum perturbation, i.e. without the use of dyes and contrast-inducing agents. These techniques probe the vibrational modes of the molecules and provide spectra that are specific to the molecular properties and chemical nature of the species.

Item Type:	Journal Article
Publication:	Current Science (Bangalore)
Publisher:	Indian Academy of Sciences
Additional Information:	Copyright of this article belongs to Indian Academy of Sciences.
Keywords:	Biomedical applications;chemometrics;Raman and infrared microspectroscopy;vibrational spectroscopy
Department/Centre:	Division of Biological Sciences > Molecular Reproduction, Development & Genetics Division of Chemical Sciences > Inorganic & Physical Chemistry
Date Deposited:	13 Mar 2012 04:54
Last Modified:	13 Mar 2012 04:54
URI:	http://eprints.iisc.ac.in/id/eprint/43712

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