ZnO/Ag nanohybrid: synthesis, characterization, synergistic antibacterial activity and its mechanism

Ghosh, Somnath and Goudar, VS and Padmalekha, KG and Bhat, SV and Indi, SS and Vasan, HN (2012) ZnO/Ag nanohybrid: synthesis, characterization, synergistic antibacterial activity and its mechanism. In: RSC Advances , 2 (3). pp. 930-940.

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Abstract

A highly homogeneous ZnO/Ag nanohybrid has been synthesized by a novel route, employing chitosan as mediator by purely electrostatic interaction. By employing various techniques such as powder XRD, UV-visible, IR spectroscopy and electron (SEM, TEM) microscopy, the formation of the nanohybrid has been established. The synergistic antibacterial effect of ZnO/Ag nanohybrid on Gram-positive and Gram-negative bacteria is found to be more effective, compared to the individual components (ZnO and Ag). Cytotoxicity experiments are carried out and the results are correlated to the solubility of the nanohybrid. A possible mechanism has been proposed for the antibacterial activity of ZnO/Ag nanohybrid, based on TEM studies on bacteria, carried out by employing the microtome technique and by EPR measurements on the hybrid.

Item Type:	Journal Article
Publication:	RSC Advances
Publisher:	Royal Society of Chemistry
Additional Information:	Copyright of this article belongs to Royal Society of Chemistry.
Department/Centre:	Division of Chemical Sciences > Solid State & Structural Chemistry Unit
Date Deposited:	15 Feb 2012 04:37
Last Modified:	15 Feb 2012 04:37
URI:	http://eprints.iisc.ac.in/id/eprint/43440

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