Hybrid systems through natural product leads: An approach towards new molecular entities

Mehta, Goverdhan and Singh, Vishwakarma (2002) Hybrid systems through natural product leads: An approach towards new molecular entities. In: Chemical Society Reviews, 31 (6). pp. 324-334.

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Abstract

Hybrid systems are constructs of different molecular entities, natural or unnatural, to generate functional molecules in which the characteristics of various components are modulated, amplified or give rise to entirely new properties. These hybrids can be designed from carefully selected components either through domain intergration of key structural/functional features or via straightforward covalent linkages. Some of the recently reported hybrid systems based on steroid, carbohydrate, C-60-fullerene platforms, amongst others, mainly crafted with the object of enhancement of the therapeutical spectrum, will be discussed.

Item Type:	Journal Article
Publication:	Chemical Society Reviews
Publisher:	Royal Society of Chemistry
Additional Information:	Copyright of this article belongs to Royal Society of Chemistry.
Department/Centre:	Division of Chemical Sciences > Organic Chemistry
Date Deposited:	19 Jul 2011 05:10
Last Modified:	19 Jul 2011 05:10
URI:	http://eprints.iisc.ac.in/id/eprint/39233

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