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Subclinical autonomic neuropathy in alcoholics: Decreased heart rate variability

Jayaprakash, MS and Ramakrishnan, AG and Murthy, PJNV and Gangadhar, BN and Janakiramaiah, N (1997) Subclinical autonomic neuropathy in alcoholics: Decreased heart rate variability. In: Nimhans Journal, 15 (3). pp. 219-223.

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Cardiac autonomic neuropathy is known to occur in alcoholics but the extent of its subclinical form is not usually recognized, Heart Rate Variability (HRV) analysis can detect subclinical autonomic neuropathy. In this study the HRV parameters were compared in 20 neurologically asymptomatic alcoholics, 20 age-matched normals and 16 depressives. All were males, ECG was recorded in a quiet room for four minutes in supine position. Time and Frequency domain parameters of HRV were computed by a researcher blind to clinical details. Alcoholics had significantly smaller Coefficient of Variation of R-R intervals (CVR-R) on time domain analysis and smaller HF band (0.15-0.5 Hz) power on spectral analysis. The decreased Heart Rate Variability indicates cardiac autonomic dysfunction.

Item Type: Journal Article
Publication: Nimhans Journal
Publisher: Natl Inst Mental Health Neuro Sciences
Additional Information: Copyright of this article belongs to Natl Inst Mental Health Neuro Sciences.
Keywords: Alcoholism/CO;Neuropathies,Hereditary Sensory and Autonomic/DI;Autonomic Nervous System Diseases/DI; Depression;Depressive Disorder;Cardiovascular System/DE; Human;Male;Adult
Department/Centre: Division of Electrical Sciences > Electrical Engineering
Date Deposited: 24 Jun 2011 05:08
Last Modified: 24 Jun 2011 05:08
URI: http://eprints.iisc.ac.in/id/eprint/38503

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