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Enantioselective total synthesis of iso-cladospolide B, cladospolide C and cladospolide B from tartaric acid

Prasad, Kavirayani R and Gandi, Vasudeva Rao (2011) Enantioselective total synthesis of iso-cladospolide B, cladospolide C and cladospolide B from tartaric acid. In: Tetrahedron: Asymmetry, 22 (5). pp. 499-505.

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Official URL: http://dx.doi.org/10.1016/j.tetasy.2011.02.018

Abstract

The enantioselective synthesis of the natural products cladospolide B, cladospolide C, and iso-cladospolide B has been accomplished from tartaric acid. Key reactions in the synthetic sequence include the elaboration of a gamma-hydroxy amide derived from tartaric acid via alkene cross metathesis, Yamaguchi lactonization, and ring closing metathesis. (C) 2011 Elsevier Ltd. All rights reserved.

Item Type: Journal Article
Publication: Tetrahedron: Asymmetry
Publisher: Elsevier Science
Additional Information: Copyright of this article belongs to Elsevier Science.
Department/Centre: Division of Chemical Sciences > Organic Chemistry
Date Deposited: 22 Jun 2011 08:25
Last Modified: 22 Jun 2011 08:25
URI: http://eprints.iisc.ac.in/id/eprint/38392

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