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Secretion of endocrine signals by the primate embryo during the peri-implantation period

Seshagiri, PB and Hearn, JP (1995) Secretion of endocrine signals by the primate embryo during the peri-implantation period. In: Current Science (Bangalore), 68 (4). pp. 373-379.

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Development of preimplantation embryos and blastocyst implantation are critical early events in the establishment of pregnancy. In primates, embryonic signals, secreted during the peri-implantation period, are believed to play a major role in the regulation of embryonic differentiation and implantation. However, only limited progress has been made in the molecular and functional characterization of embryonic signals, partly due to severe paucity of primate embryos and the lack of optimal culture conditions to obtain viable embryo development. Two embryonic (endocrine) secretions, i.e. chorionic gonadotrophin (CG) and gonadotrophin releasing hormone (GnRH) are being studied. This article reviews the current status of knowledge on the recovery and culture of embryos, their secretion of CG, GnRH and other potential endocrine signals and their regulation and physiological role(s) during the peri-implantation period in primates, including humans.

Item Type: Journal Article
Publication: Current Science (Bangalore)
Publisher: Indian Academy of Sciences
Additional Information: Copyright of this article belongs to Indian Academy of Sciences.
Department/Centre: Division of Biological Sciences > Molecular Reproduction, Development & Genetics
Date Deposited: 26 May 2011 10:00
Last Modified: 02 Nov 2011 05:43
URI: http://eprints.iisc.ac.in/id/eprint/37889

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