Kala, KC and Antony, A (1995) Antibodies raised against guanosine bind to double-stranded DNA. In: Biochemistry & Molecular Biology International, 37 (2). pp. 305-312.
Full text not available from this repository. (Request a copy)Abstract
Antibodies elicited against guanosine have been reported to bind to single-stranded DNA. Using an avidin-biotin microELISA, we report that these antibodies also bind to double-stranded DNA. The binding is specific and is completely inhibited by the homologous hapten. The cross-reactivity of double-stranded DNA binding antibodies to single-stranded DNA is low. The antibodies are shown to bind to the topoisomers of plasmid DNA as assessed by a gel retardation assay.
| Item Type: | Journal Article |
|---|---|
| Publication: | Biochemistry & Molecular Biology International |
| Publisher: | Academic Press Aust |
| Additional Information: | Copyright of this article belongs to Academic Press Aust. |
| Department/Centre: | Division of Biological Sciences > Microbiology & Cell Biology |
| Date Deposited: | 26 Apr 2011 06:21 |
| Last Modified: | 26 Apr 2011 06:21 |
| URI: | http://eprints.iisc.ac.in/id/eprint/36918 |
Actions (login required)
 |
View Item |
