A Study of Long-range Correlations in Schizophrenia EEG using Detrended Fluctuation Analysis

Raghavendra, BS and Narayana D, Dutt (2010) A Study of Long-range Correlations in Schizophrenia EEG using Detrended Fluctuation Analysis. In: International Conference on Signal Processing and Communications, JUL 18-21, 2010, Indian Inst Sci, Bangalore, INDIA.

PDF A_Study.pdf - Published Version Restricted to Registered users only Download (147kB) | Request a copy

Abstract

In this paper, we have studied electroencephalogram (EEG) activity of schizophrenia patients, in resting eyes closed condition, with detrended fluctuation analysis (DFA). The DFA gives information about scaling and long-range correlations in time series. We computed DFA exponents from 30 scalp locations of 18 male neuroleptic-naIve, recent-onset schizophrenia (NRS) subjects and 15 healthy male control subjects. Our results have shown two scaling regions in all the scalp locations in all the subjects, with different slopes, corresponding to two scaling exponents. No significant differences between the groups were found with first scaling exponent (short-range). However, the second scaling exponent (long-range) were significantly lower in control subjects at all scalp locations (p<0.05, Kruskal-Wallis test). These findings suggest that the long-range scaling behavior of EEG is sensitive to schizophrenia, and this may provide an additional insight into the brain dysfunction in schizophrenia.

Item Type:	Conference Paper
Publisher:	IEEE
Additional Information:	Copyright 2010 IEEE. Personal use of this material is permitted.However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from the IEEE.
Department/Centre:	Division of Electrical Sciences > Electrical Communication Engineering
Date Deposited:	06 Apr 2011 11:46
Last Modified:	06 Apr 2011 11:46
URI:	http://eprints.iisc.ac.in/id/eprint/36374

Actions (login required)

View Item