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Synthesis of Isoquinolines from Indanones-Total Synthesis of Illudinine

Shanker, PS and Rao, GSRS (1993) Synthesis of Isoquinolines from Indanones-Total Synthesis of Illudinine. In: Indian Journal of Chemistry - Section B: Organic and Medicinal Chemistry, 32 (12). 1209-1213 .

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Abstract

Schmidt reaction of 5-methoxy or 7-methoxyindan-1-ones or their derivatives results exclusively in isocarbostyrils which are converted into 6-methoxy or 8-methoxyisoquinolines in good yields. This strategy has been extended to the total synthesis of illudinine methyl ester (1b) starting from methyl 8-methoxy-2,2-dimethyl-7-oxo-1,2,3,5,6,7-hexahydro-s-indacene-4-carboxylate (4).

Item Type: Journal Article
Publication: Indian Journal of Chemistry - Section B: Organic and Medicinal Chemistry
Publisher: National Institute of Science Communication and Information Resources
Additional Information: Copyright of this article belongs to National Institute of Science Communication and Information Resources.
Department/Centre: Division of Chemical Sciences > Organic Chemistry
Date Deposited: 10 Mar 2011 07:00
Last Modified: 10 Mar 2011 07:00
URI: http://eprints.iisc.ac.in/id/eprint/35860

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