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Synthesis of substituted 8-aminoquinolines and phenanthrolines through a Povarov approach

De, Kavita and Legros, Julien and Crousse, Benoit and Chandrasekaran, Srinivasan and Bonnet-Delpona, Daniele (2011) Synthesis of substituted 8-aminoquinolines and phenanthrolines through a Povarov approach. In: Organic and Biomolecular Chemistry, 9 (2). pp. 347-350.

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Abstract

The synthesis of 8-aminoquinolines and 1,10-phenanthrolines with substituents in alpha of the nitrogen has been performed through an inverse-demanding aza-Diels-Alder (Povarov reaction) in the fluoroalcohols TFE or HFIP. This path involves simple starting materials: 1,2-phenylenediamines, enol ethers and aldehydes.

Item Type: Journal Article
Publication: Organic and Biomolecular Chemistry
Publisher: Royal Society of Chemistry
Additional Information: Copyright of this article belongs to Royal Society of Chemistry.
Department/Centre: Division of Chemical Sciences > Organic Chemistry
Date Deposited: 03 Mar 2011 12:32
Last Modified: 03 Mar 2011 12:32
URI: http://eprints.iisc.ac.in/id/eprint/35795

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