Sriramarao, P and Selvakumar, B and Damodaran, C and RAO, BSS and Prakash, O and Rao, PVS (1990) Immediate hypersensitivity to Parthenium hysterophorus. I. Association of HLA antigens and Parthenium rhinitis. In: Clinical and Experimental Allergy, 20 (5). pp. 555-560.
Full text not available from this repository. (Request a copy)Abstract
Lymphocytes collected from rhinitis subjects with strong positive skin reactions to the pollen allergens of Parthenium hysterophorus (American feverfew) having moderate to high titres of Parthenium-specific serum IgE were analysed for association of HLA-antigens covering 13 specificities of HLA-A, 17 specificities of HLA-B and eight specificities of HLA-DR loci by the NIH two-stage microlymphocytotoxicity assay. Comparison of the phenotypic frequencies of HLA-A and B antigens between Parthenium rhinitis subjects (n= 22) and control subjects (n= 137) did not suggest any significant association when tested for these antigen specificities. A significant correlation in the association of HLA-DR3 antigen with a relative risk of 11·33, however, was observed in Parthenium rhinitis subjects (n= 30) when compared to controls (n= 50).
| Item Type: | Journal Article |
|---|---|
| Publication: | Clinical and Experimental Allergy |
| Publisher: | John Wiley & Sons |
| Additional Information: | Copyright of this article belongs to John Wiley & Sons. |
| Department/Centre: | Division of Biological Sciences > Biochemistry |
| Date Deposited: | 26 Apr 2011 10:41 |
| Last Modified: | 23 Oct 2018 08:30 |
| URI: | http://eprints.iisc.ac.in/id/eprint/35063 |
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