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Asymmetric synthesis of \alpha-methoxyarylacetic acid derivatives

Prasad, Kavirayani R and Chandrakumar, Appayee (2005) Asymmetric synthesis of \alpha-methoxyarylacetic acid derivatives. In: Tetrahedron: Asymmetry, 16 (11). pp. 1897-1900.


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Stereoselective synthesis of a series of 2-aryl-2-methoxyethanols was achieved from inexpensive chiral pool tartaric acid employing a diastereoselective reduction of a symmetrical 1,4-diaryldiketone as the key step. 2-Aryl-2-methoxyethanols were enantioselectively prepared in 80-90% yield.

Item Type: Journal Article
Publication: Tetrahedron: Asymmetry
Publisher: Pergamon-Elsevier Science Ltd
Additional Information: Copyright for this article belongs to Elsevier.
Department/Centre: Division of Chemical Sciences > Organic Chemistry
Date Deposited: 28 Jul 2005
Last Modified: 19 Sep 2010 04:19
URI: http://eprints.iisc.ac.in/id/eprint/3462

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