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Reproductive behavior and health in consanguineous marriages

Bittles, AH and Mason, MW and Greene, J and Rao, NA (1991) Reproductive behavior and health in consanguineous marriages. In: Science, 252 (5007). 789 -794.

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Official URL: http://www.sciencemag.org/content/252/5007/789.abs...


In many regions of Asia and Africa, consanguineous marriages currently account for approximately 20 to 50% of all unions, and preliminary observations indicate that migrants from these areas continue to contract marriages with close relatives when resident in North America and Western Europe. Consanguinity is associated with increased gross fertility, due at least in part to younger maternal age at first livebirth. Morbidity and mortality also may be elevated, resulting in comparable numbers of surviving offspring in consanguineous and nonconsanguineous families. With advances in medicine and public health, genetic disorders will account for an increased proportion of disease worldwide. Predictably, this burden will fall more heavily on countries and communities in which consanguinity is strongly favored, as the result of the expression of deleterious recessive genes. However, studies conducted in such populations indicate that the adverse effects associated with inbreeding are experienced by a minority of families.

Item Type: Journal Article
Publication: Science
Publisher: American Association for the Advancement of Science
Additional Information: Copyright of this article belongs to American Association for the Advancement of Science.
Keywords: South-India; Parental Consanguinity; Prereproductive Mortality;Genetic-Disease;Tamil-Nadu;Congenital-Abnormalities;Parnetal Consanguinity;Postnatal Mortality; Fetal Growth;Japan.
Department/Centre: Division of Biological Sciences > Biochemistry
Date Deposited: 30 Nov 2010 06:40
Last Modified: 30 Nov 2010 06:40
URI: http://eprints.iisc.ac.in/id/eprint/34111

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