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Visiting the cell biology of Salmonella infection

Lahiri, Amit and Lahiri, Ayan and Iyer, Namrata and Das, Priyanka and Chakravortty, Dipshikha (2010) Visiting the cell biology of Salmonella infection. In: Microbes and Infection, 12 (11). pp. 809-818.

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Official URL: http://dx.doi.org/10.1016/j.micinf.2010.05.010


Salmonella, a Gram-negative facultative intracellular pathogen is capable of infecting vast array of hosts. The striking ability of Salmonella to overcome every hurdle encountered in the host proves that they are true survivors. In the host, Salmonella infects various cell types and needs to survive and replicate by countering the defense mechanism of the specific cell. In this review, we will summarize the recent insights into the cell biology of Salmonella infection. Here, we will focus on the findings that deal with the specific mechanism of various cell types to control Salmonella infection. Further, the survival strategies of the pathogen in response to the host immunity will also be discussed in detail. Better understanding of the mechanisms by which Salmonella evade the host defense system and establish pathogenesis will be critical in disease management. (C) 2010 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.

Item Type: Journal Article
Publication: Microbes and Infection
Publisher: Elsevier Science B.V.
Additional Information: Copyright of this article belongs to Elsevier Science B.V.
Keywords: Salmonella serovars; M cells; Macrophages; Dendritic cells; Epithelial cells; Pathogenesis
Department/Centre: Division of Biological Sciences > Microbiology & Cell Biology
Date Deposited: 29 Nov 2010 11:26
Last Modified: 29 Nov 2010 11:26
URI: http://eprints.iisc.ac.in/id/eprint/34066

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