Nagpal, Sunil and Namboodiri, MSA and Rao, Subba BS and Rao, Subba PV (1991) IgG4 Autoantibodies to DNA in Systemic Lupus erythematosus Patients. In: International Archives of Allergy & Applied Immunology, 95 (1). pp. 1-6.
Full text not available from this repository. (Request a copy)Abstract
The presence of DNA-specific IgG4 antibodies was demonstrated in the sera of patients with systemic lupus erythematosus (SLE) by a microtiter solid-phase radioimmunoassay. A patient with distal inter-phalangeal swelling and extensive ulcers in the oral cavity, seronegative for anti-DNA antibodies of the IgG isotype, was found to have anti-DNA autoantibodies exclusively of the IgG4 subclass. These autoantibodies directed against the dsDNA conformation cross-reacted with chondroitin sulfate, dermatan sulfate and heparin.
| Item Type: | Journal Article |
|---|---|
| Publication: | International Archives of Allergy & Applied Immunology |
| Publisher: | Karger, Allschwilerstrasse |
| Additional Information: | Copyright of this article belongs to Karger, Allschwilerstrasse. |
| Keywords: | Subclass Distribution;Antibodies;Serum;Glomerulonephritis; Chromatography;Nephritis;Diseases. |
| Department/Centre: | Division of Biological Sciences > Biochemistry |
| Date Deposited: | 18 Nov 2010 10:46 |
| Last Modified: | 18 Nov 2010 10:46 |
| URI: | http://eprints.iisc.ac.in/id/eprint/33872 |
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