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Characterization of foot-and-mouth disease virus types Ο and Asia 1 RNA

Vasantha, S and LAL, SM and Antony, A (1988) Characterization of foot-and-mouth disease virus types Ο and Asia 1 RNA. In: Journal of Biosciences, 13 (1). 39 -42.

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Foot-and-mouth disease is an acute and highly contagious febrile disease affecting cloven-footed animals. Identification of the foot-and-mouth disease virus (FMDV), the causative agent of the disease, posed problems because of the occurrence of many types and subtypes of the virus. A molecular approach based on oligonucleotide mapping of FMDV RNA has been used for the identification and characterization of virus isolates obtained in a disease outbreak (King et al., 1981). One-dimensional oligonucleotide mapping was used for rapid analysis of FMDV RNA (LaTorre et al., 1982). FMDV types Ο and Asia 1 of Indian origin are being routinely used for vaccine production in India. This report presents the differences between FMDV types Ο and Asia 1 at molecular level based on one-dimensional oligonucleotide mapping of virus-induced poly (A) RNA.

Item Type: Journal Article
Publication: Journal of Biosciences
Publisher: Indian Academy of Sciences
Additional Information: Copyright of this article belongs to Indian Academy of Sciences.
Keywords: Foot-and-mouth disease virus;poly (A) RNA;oligo (dT)-cellulose chromatography;oligonucleotide mapping;base composition analysis.
Department/Centre: Division of Biological Sciences > Microbiology & Cell Biology
Date Deposited: 06 Sep 2010 10:22
Last Modified: 19 Sep 2010 06:16
URI: http://eprints.iisc.ac.in/id/eprint/32064

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