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Biotransformations of α-terpineol in the rat: Its effects on the liver microsomal cytochrome P-450 system

Madyastha, Madhava K and Srivatsan, V (1988) Biotransformations of α-terpineol in the rat: Its effects on the liver microsomal cytochrome P-450 system. In: Bulletin of Environmental Contamination and Toxicology, 41 (1). pp. 17-25.

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Abstract

Alpha-Terpineol (I), a monocyclic monoterpene tertiary alcohol, is widely used in the manufacture of perfumes, cosmetics, soaps and antiseptic agents. It was reported earlier (Horning et al. 1976) that this monoterpene alcohol when administered to humans is hydroxylated to p-menth-l,2,8-triol (II). It is not known whether c~-terpineol also produces other metabolites during its metabolism in the mammalian system and if so, the nature of these metabolites.

Item Type: Journal Article
Publication: Bulletin of Environmental Contamination and Toxicology
Publisher: Springer
Additional Information: Copyright of this article belongs to Springer.
Department/Centre: Division of Chemical Sciences > Organic Chemistry
Date Deposited: 06 Sep 2010 09:57
Last Modified: 19 Sep 2010 06:16
URI: http://eprints.iisc.ac.in/id/eprint/32051

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