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Deamidation of nicotinamide and NMN

Sarma, DSR and Rajalakshmi, S and Sarma, PS (1961) Deamidation of nicotinamide and NMN. In: Biochemical and Biophysical Research Communications, 6 (5). pp. 389-393.

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Official URL: http://dx.doi.org/10.1016/0006-291X(61)90151-6


Deamidation of nicotinamide was first demonstrated in lactic acid bacteria by Hughes and Williamson (1953). Rajagopalan et al. (1958) were the first to report the presence of this enzyme nicotinamide deamidase in vertebrates. Among the vertebrates studied, the enzyme activity was exhibited only by the avian species. The present communication deals with, 1) a detailed survey of distribution of nicotinamide deamidases in avain species, and 2) for the first time, deamidation of nicotinamide at nucleotide level by mouse liver. Further, a possible biological role for deamidases was suggested. Experimental details were similar to that reported by Rajagopalan et al. (1959).

Item Type: Journal Article
Publication: Biochemical and Biophysical Research Communications
Publisher: Elsevier Science
Additional Information: Copyright of this article belongs to Elsevier Science.
Department/Centre: Division of Biological Sciences > Biochemistry
Date Deposited: 15 Jun 2010 12:27
Last Modified: 19 Sep 2010 06:09
URI: http://eprints.iisc.ac.in/id/eprint/28417

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