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Effect of ICSH on Early Pregnancy in Hypophysectomized Pregnant Rats

Moudgal, NR (1969) Effect of ICSH on Early Pregnancy in Hypophysectomized Pregnant Rats. In: Nature, 222 (5190). pp. 286-287.

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Official URL: http://www.nature.com/nature/journal/v222/n5190/ab...


Moudgal and co-workers1-3 recently reported that the administration to intact pregnant rats of rabbit antiserum ovine interstitial cell stimulating hormone (ICSH) on any one day between the eighth and twelfth days of pregnancy resulted in resorption of foetuses and termination of pregnancy. This effect was readily reversed by the simultaneous administration of progesterone but not by oestradiol-17β. These observations suggested that ICSH was involved in progesterone synthesis and as such is a luteotropic factor in the rat.

Item Type: Editorials/Short Communications
Publication: Nature
Publisher: Nature Publishing Group
Additional Information: Copyright of this article belongs to Nature Publishing Group.
Department/Centre: Division of Biological Sciences > Biochemistry
Date Deposited: 18 May 2010 06:12
Last Modified: 18 May 2010 06:12
URI: http://eprints.iisc.ac.in/id/eprint/27598

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