Polycyclitols: synthesis of novel carbasugar and conduritol analogues as potential glycosidase inhibitors

Mehta, Goverdhan and Ramesh, Senaiar S (2001) Polycyclitols: synthesis of novel carbasugar and conduritol analogues as potential glycosidase inhibitors. In: Tetrahedron Letters, 42 (10). pp. 1987-1990.

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Abstract

Stereoselective syntheses of a new family of hydrindane based bicyclitols with seven hydroxyl groups in a diverse stereochemical array have been accomplished from readily available building-blocks. One of the bicyclitols 12 has been found to exhibit moderate a-glucosidase inhibitory activity in enzymatic assays.

Item Type:	Journal Article
Publication:	Tetrahedron Letters
Publisher:	Elsevier Science
Additional Information:	Copyright for this article belongs to Elsevier Science.
Department/Centre:	Division of Chemical Sciences > Organic Chemistry
Date Deposited:	01 Feb 2005
Last Modified:	19 Sep 2010 04:17
URI:	http://eprints.iisc.ac.in/id/eprint/2690

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