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A simple model for protein thermal denaturation

Bandekar, J (1978) A simple model for protein thermal denaturation. In: International Journal of Peptide & Protein Research, 11 (1). pp. 191-193.

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Official URL: http://www.ncbi.nlm.nih.gov/pubmed/649254


Whether proteins denature in all-or-none fashion or in a continuous fashion is as yet an unresolved problem. The all-or-none process implies that while the process of denaturation is going on, only two kinds of protein molecules can exist. One is completely unchanged and the other is altered. The altered protein molecules are indistinguishable. Underlying the 'continuum' models is the assumption that all the chains in a protein globule undergo similar changes so that it is enough to consider a single chain.

Item Type: Journal Article
Publication: International Journal of Peptide & Protein Research
Publisher: Munksgaard Int Publ Ltd,
Additional Information: Copyright of this article belongs to Munksgaard Int Publ Ltd.
Department/Centre: Division of Chemical Sciences > Solid State & Structural Chemistry Unit
Date Deposited: 16 Dec 2009 11:59
Last Modified: 16 Dec 2009 11:59
URI: http://eprints.iisc.ac.in/id/eprint/24900

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