Interaction of palladium (II) with DNA

Pillai, CKS and Nandi, US (1977) Interaction of palladium (II) with DNA. In: Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 474 (1). pp. 11-16.

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Abstract

The nature of interaction of palladium(II) with calf thymus DNA was studied using viscometry, ultraviolet, visible and infrared spectrophotometry and optical rotatory disperison and circular dichroism measurements. The results indicate that Pd(II) interacts with both the phosphate and bases of DNA. The ORD/CD data indicate that the binding of Pd(II) to DNA brings about considerable conformational changes in DNA.

Item Type:	Journal Article
Publication:	Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis
Publisher:	Elsevier Science
Additional Information:	Copyright of this article belongs to Elsevier Science
Department/Centre:	Division of Chemical Sciences > Inorganic & Physical Chemistry
Date Deposited:	04 Feb 2010 07:26
Last Modified:	19 Sep 2010 05:50
URI:	http://eprints.iisc.ac.in/id/eprint/24464

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