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Hydrolysis of sphingomyelin to ceramide with hydrofluoric acid

Reddy, PV and Natarajan, V and Sastry, PS (1976) Hydrolysis of sphingomyelin to ceramide with hydrofluoric acid. In: Chemistry and Physics of Lipids, 17 (2-3). pp. 373-377.

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Sphingomyelin was hydrolyzed to ceramide near quantitatively on treatment with 40% HF at 40°C for 72 hr. The reaction of sphingomyelin with HF is much slower than phosphoglycerides. HF treatment did not alter either the fatty acid composition or the stereochemical configuration of the sphingosine moiety of ceramide formed.

Item Type: Journal Article
Publication: Chemistry and Physics of Lipids
Publisher: Elsevier Science
Additional Information: Copyright of this article belongs to Elsevier Science.
Department/Centre: Division of Biological Sciences > Biochemistry
Date Deposited: 11 Dec 2009 09:33
Last Modified: 19 Sep 2010 05:48
URI: http://eprints.iisc.ac.in/id/eprint/23933

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