Molecular structures of cytidine-5-diphosphate and cytidine-5-diphospho-choline, and their role in intermediary metabolism

Viswamitrata, MA and Seshadri, TP and Post, ML and Kennard, Olga (1975) Molecular structures of cytidine-5-diphosphate and cytidine-5-diphospho-choline, and their role in intermediary metabolism. In: Nature, 258 (5535). pp. 497-501.

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Abstract

The nucleotide coenzyme cytidine-5-diphospho-choline is highly folded. The CMP-5 parts of the molecules in the crystal structure are strongly linked by metal ligation and hydrogen bonds leaving the phosphoryl-choline residues relatively free. Cytidine-5-diphosphoric acid exists as a zwitterion with N31 protonated. The P−O bond lengths from the anhydride bridging oxygen in the pyrophosphate are significantly different.

Item Type:	Journal Article
Publication:	Nature
Publisher:	Nature Publishing Group
Additional Information:	Copyright of this article belongs to Nature Publishing Group.
Department/Centre:	Division of Physical & Mathematical Sciences > Physics
Date Deposited:	22 Jan 2010 07:00
Last Modified:	27 Apr 2017 09:24
URI:	http://eprints.iisc.ac.in/id/eprint/23788

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