Hosur, Ramakrishna V and Govi, Girjesh and Hosur, Madhusoodan V and Viswamitra, MA (1981) Sequence effects in structures of the dinucleotides d-pApT AND d-pTpA. In: Journal of Molecular Structure, 72 (Mar). pp. 261-267.
PDF
full_text_9.pdf - Published Version Restricted to Registered users only Download (497kB) | Request a copy |
Abstract
The H1',H2' and H2″ regions of the 270-MHz PMR spectra of two deoxydinucleotides, d-pTpA and d-pApT, have been analyzed. The coupling constants in the sugar ring indicate that both A and T sugars have a tendency to acquire 2E conformations. There is also a marginal difference in the 2E populations of the T sugar in the two dinucleotides. The trends in the chemical shifts of base protons indicate different stacking of the bases in d-pApT and d-pTpA. The sequence effects on base stacking and pentose conformation are discussed.
Item Type: | Journal Article |
---|---|
Publication: | Journal of Molecular Structure |
Publisher: | Elsevier Science |
Additional Information: | Copyright of this article belongs to Elsevier Science. |
Department/Centre: | Division of Physical & Mathematical Sciences > Physics |
Date Deposited: | 24 Dec 2009 09:31 |
Last Modified: | 19 Sep 2010 05:47 |
URI: | http://eprints.iisc.ac.in/id/eprint/23767 |
Actions (login required)
View Item |