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Specificity of anti-nucleoside antibodies

Humayun, Mir Z and Jacob, T Mathai (1974) Specificity of anti-nucleoside antibodies. In: Biochemical Journal, 141 (1). pp. 313-315.

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The method of conjugation of a nucleoside or related compound to a carrier protein may have a significant effect on the specificity of the antibodies elicited. It is demonstrated, by means of the membrane-filtration assay, that anti-isopentenyladenosine antibodies produced by the `periodate procedure' are much more reactive with the periodate-oxidized form of the nucleoside than with the parent compound. In addition, the simplicity and specificity of the assay used suggests its use as a sensitive radioimmunoassay for this multifunctional nucleoside.

Item Type: Journal Article
Publication: Biochemical Journal
Publisher: Portland Press
Additional Information: copyright of this article belongs to Portland Press.
Department/Centre: Division of Biological Sciences > Biochemistry
Date Deposited: 19 Dec 2009 06:59
Last Modified: 19 Sep 2010 05:46
URI: http://eprints.iisc.ac.in/id/eprint/23609

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