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ESR study of metal ion-guanosine monophosphate interaction

Podder, SK and Rengan, S Kasthuri and Navalgund, Ranganath (1974) ESR study of metal ion-guanosine monophosphate interaction. In: Journal of Magnetic Resonance, 15 (2). pp. 254-261.

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The addition of guanosine 5-monophosphate (5′-GMP) to an aqueous solution of Mn2+ ions results in a decrease in ESR signal intensity and an increase in line-width of Mn2+ ions. This can be interpreted in terms of stepwise formation of outersphere and inner-sphere complexes as When Mg2+ is added to a mixture of Mn2+ and 5′-GMP, ESR signal intensity increases, presumably due to the replacement of Mn2+ by Mg2+ in the complex. From the variation of ESR signal intensity as a function of concentration of Mg2+, the product K1K2 for the magnesium complex i s calculated as 125 M−1. This difference in stability constants may indicate that both phosphate group and guanine base are involved in the formation of Mn2+-5′-GMP complex.

Item Type: Journal Article
Publication: Journal of Magnetic Resonance
Publisher: Elsevier Science
Additional Information: Copyright of this article belongs to Elsevier Science.
Department/Centre: Division of Biological Sciences > Biochemistry
Date Deposited: 21 Dec 2009 10:32
Last Modified: 19 Sep 2010 05:44
URI: http://eprints.iisc.ac.in/id/eprint/23164

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